Not only did these trials prove the effectiveness of the new drugs, but they also answered important additional questions about whether the drugs should be given in combination or in sequence with others, the likelihood of side effects with long-term use, and patients’ overall quality of life.
These trials gave women with ER-positive early breast cancer more treatment options than tamoxifen alone, and hence contribute to improving the quality of life for countless women around the globe, an important step forward towards personalised treatments for women with ER-positive disease.