HERA

Un nouveau traitement standard pour le cancer du sein HER2+

Female patient receiving IV from doctor

Recruiting 5,102 women from 480 sites across 39 countries in just over four years – in itself a remarkable achievement – HERA contributed to a new standard of treatment for women with HER2-positive, early breast cancer, a highly aggressive form of the disease.

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Female chest, symbol illustrating women diagnosed with breast cancer
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Microscope, symbol illustrating research
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Globe, symbol illustrating international collaboration
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Stethoscop, symbol illustrating breast cancer experts
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Les principaux résultats de l’étude, publiés en 2005 et en 2017, ont indiqué qu’un an de traitement avec trastuzumab apportait un bénéfice significatif et durable pour la prévention des récidives du cancer et l’amélioration globale de la survie pour ce groupe de patients.

Coordinated by BIG, the Institut Jules Bordet – Clinical Trials Support Unit, and Frontier Science Scotland in collaboration with Roche, HERA involved the participation of 27 BIG collaborative groups and  helped accelerate the approval of trastuzumab, becoming a standard treatment for HER2-positive breast cancer.

Cette étude a déjà permis à plus de 2 millions The Lancet in April 2017 and showed that both the risk of recurrence and of death were reduced by 25% over time. As noted in the paper, to our knowledge, this 11-year follow-up provides the longest survival data of any trial that assessed the addition of anti-HER2 therapy to standard treatment for HER2-positive early breast cancer.

Aidez-nous à sauver des vies et à faire avancer la recherche sur le cancer du sein